Featured Publications

"Brain gene co-expression networks link complement signaling with convergent synaptic pathology in schizophrenia". Minsoo Kim, Jillian R. Haney, Pan Zhang, Leanna M. Hernandez, Lee-kai Wang, Laura Perez-Cano, Loes M. Olde Loohuis, Luis de la Torre-Ubieta & Michael J. Gandal (2021).  Nature Neuroscience. 

"Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder"  Gandal MJ*, Zhang P, Hadjimichael E, Walker RL, Chen C, … , PsychENCODE Consortium, White K, Peters MA, Gerstein M, Liu C*, Iakoucheva LM*, Pinto D*, Geschwind DH*. Science. 362(6420), 2018.

• Spectrum Notable Papers in 2019
• Coverage in: The Scientist, NIH Research Matters, 

"Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap" Gandal MJ, Haney JR, Parikshak NN, Leppa V, Ramaswami G, Hartl C, Schork AJ, Appadurai V, Buil A, Werge TM, Liu C, White KP, CommonMind Consortium, PsychENCODE Consortium, iPSYCH-BROAD Working Group, Horvath S, Geschwind DH.  Science. 359(6376):693-697, 2018

• Spectrum News Notable Papers in 2018
• Autism Speaks Top 10 Papers of 2018
• Coverage by: Scientific American, CNN, New Scientist, Washington Post, NPR

• Arjun Bhattacharya, Connor Jops, Minsoo Kim, Cindy Wen, Daniel D. Vo, Jonatan L. Hervoso, Bogdan Pasaniuc, Michael J. Gandal. "Isoform-level transcriptome-wide association uncovers extensive novel genetic risk mechanisms for neuropsychiatric disorders in the human brain" medRxiv 2022.08.23.22279134; doi: https://doi.org/10.1101/2022.08.23.22279134

• Michael Gandal, Jillian R. Haney, Brie Wamsley, George T. Chen, Sepideh Parhami, Prashant S. Emani, Nathan Chang, Gil D. Hoftman, Diego de Alba, Gaurav Kale, Gokul Ramaswami, Christopher L. Hartl, Ting Jin, Daifeng Wang, Jing Ou, Ye Emily Wu, Neelroop N. Parikshak, Vivek Swarup, T. Grant Belgard, Mark Gerstein, Bogdan Pasaniuc, Daniel H. Geschwind. "Broad transcriptomic dysregulation across the cerebral cortex in ASD" bioRxiv
• Leanna M. Hernandez, Minsoo Kim, Pan Zhang et al. "Multi-ethnic, phenome-wide association of complement component 4 variation with psychiatric and brain developmental phenotypes in youth," Research Square. https://dx.doi.org/10.21203/rs.3.rs-1578682/v1
• Minsoo Kim, Connor T. Jops, Michael J. Gandal. "GeneticsMakie.jl: A versatile and scalable toolkit for visualizing locus-level genetic and genomic data" bioRxiv 2022.04.18.488573

• White matter microstructure shows sex differences in late childhood: Evidence from 6797 children.
  Human brain mapping. 2023 Feb 1;44(2):535-548 Epub 2022 Sep 29; Authors: Lawrence KE, Abaryan Z, Laltoo E, Hernandez LM, Gandal MJ, McCracken JT, Thompson PM
• GeneticsMakie.jl: a versatile and scalable toolkit for visualizing locus-level genetic and genomic data.
  Bioinformatics (Oxford, England). 2023 Jan 1;39(1); Authors: Kim M, Vo DD, Kumagai ME, Jops CT, Gandal MJ
• Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans.
  JAMA psychiatry. 2022 Dec 14; Authors: Kimbrel NA, Ashley-Koch AE, Qin XJ, Lindquist JH, Garrett ME, Dennis MF, Hair LP, Huffman JE, Jacobson DA, Madduri RK, Trafton JA, Coon H, Docherty AR, Mullins N, Ruderfer DM, Harvey PD, McMahon BH, Oslin DW, Beckham JC, Hauser ER, Hauser MA, Million Veteran Program Suicide Exemplar Workgroup, the International Suicide Genetics Consortium, the Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center Workgroup, and the Veterans Affairs Million Veteran Program
• Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD.
  Nature. 2022 Nov;611(7936):532-539 Epub 2022 Nov 2; Authors: Gandal MJ, Haney JR, Wamsley B, Yap CX, Parhami S, Emani PS, Chang N, Chen GT, Hoftman GD, de Alba D, Ramaswami G, Hartl CL, Bhattacharya A, Luo C, Jin T, Wang D, Kawaguchi R, Quintero D, Ou J, Wu YE, Parikshak NN, Swarup V, Belgard TG, Gerstein M, Pasaniuc B, Geschwind DH
• A Critical Appraisal of Imaging Transcriptomics.
  Biological psychiatry global open science. 2022 Oct;2(4):311-313 Epub 2022 Oct 14; Authors: Mandal AS, Gandal M, Seidlitz J, Alexander-Bloch A
• TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids.
  Stem cell reports. 2022 Oct 11;17(10):2220-2238 Epub 2022 Sep 29; Authors: Watanabe M, Buth JE, Haney JR, Vishlaghi N, Turcios F, Elahi LS, Gu W, Pearson CA, Kurdian A, Baliaouri NV, Collier AJ, Miranda OA, Dunn N, Chen D, Sabri S, Torre-Ubieta L, Clark AT, Plath K, Christofk HR, Kornblum HI, Gandal MJ, Novitch BG
• Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data.
  Nature genetics. 2022 Oct;54(10):1572-1580 Epub 2022 Sep 1; Authors: Zhang MJ, Hou K, Dey KK, Sakaue S, Jagadeesh KA, Weinand K, Taychameekiatchai A, Rao P, Pisco AO, Zou J, Wang B, Gandal M, Raychaudhuri S, Pasaniuc B, Price AL
• Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review.
  Molecular psychiatry. 2022 Sep 19; Authors: Hoffman GE, Jaffe AE, Gandal MJ, Collado-Torres L, Sieberts SK, Devlin B, Geschwind DH, Weinberger DR, Roussos P
• Association between resting-state functional brain connectivity and gene expression is altered in autism spectrum disorder.
  Nature communications. 2022 Jun 9;13(1):3328; Authors: Berto S, Treacher AH, Caglayan E, Luo D, Haney JR, Gandal MJ, Geschwind DH, Montillo AA, Konopka G
• Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
  Nature. 2022 Apr;604(7906):502-508 Epub 2022 Apr 8; Authors: Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G, Zhang W, Adams M, Agartz I, Atkinson EG, Agerbo E, Al Eissa M, Albus M, Alexander M, Alizadeh BZ, Alptekin K, Als TD, Amin F, Arolt V, Arrojo M, Athanasiu L, Azevedo MH, Bacanu SA, Bass NJ, Begemann M, Belliveau RA, Bene J, Benyamin B, Bergen SE, Blasi G, Bobes J, Bonassi S, Braun A, Bressan RA, Bromet EJ, Bruggeman R, Buckley PF, Buckner RL, Bybjerg-Grauholm J, Cahn W, Cairns MJ, Calkins ME, Carr VJ, Castle D, Catts SV, Chambert KD, Chan RCK, Chaumette B, Cheng W, Cheung EFC, Chong SA, Cohen D, Consoli A, Cordeiro Q, Costas J, Curtis C, Davidson M, Davis KL, de Haan L, Degenhardt F, DeLisi LE, Demontis D, Dickerson F, Dikeos D, Dinan T, Djurovic S, Duan J, Ducci G, Dudbridge F, Eriksson JG, Fañanás L, Faraone SV, Fiorentino A, Forstner A, Frank J, Freimer NB, Fromer M, Frustaci A, Gadelha A, Genovese G, Gershon ES, Giannitelli M, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, González Peñas J, González-Pinto A, Gopal S, Gratten J, Green MF, Greenwood TA, Guillin O, Gülöksüz S, Gur RE, Gur RC, Gutiérrez B, Hahn E, Hakonarson H, Haroutunian V, Hartmann AM, Harvey C, Hayward C, Henskens FA, Herms S, Hoffmann P, Howrigan DP, Ikeda M, Iyegbe C, Joa I, Julià A, Kähler AK, Kam-Thong T, Kamatani Y, Karachanak-Yankova S, Kebir O, Keller MC, Kelly BJ, Khrunin A, Kim SW, Klovins J, Kondratiev N, Konte B, Kraft J, Kubo M, Kučinskas V, Kučinskiene ZA, Kusumawardhani A, Kuzelova-Ptackova H, Landi S, Lazzeroni LC, Lee PH, Legge SE, Lehrer DS, Lencer R, Lerer B, Li M, Lieberman J, Light GA, Limborska S, Liu CM, Lönnqvist J, Loughland CM, Lubinski J, Luykx JJ, Lynham A, Macek M Jr, Mackinnon A, Magnusson PKE, Maher BS, Maier W, Malaspina D, Mallet J, Marder SR, Marsal S, Martin AR, Martorell L, Mattheisen M, McCarley RW, McDonald C, McGrath JJ, Medeiros H, Meier S, Melegh B, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mitjans M, Molden E, Molina E, Molto MD, Mondelli V, Moreno C, Morley CP, Muntané G, Murphy KC, Myin-Germeys I, Nenadić I, Nestadt G, Nikitina-Zake L, Noto C, Nuechterlein KH, O'Brien NL, O'Neill FA, Oh SY, Olincy A, Ota VK, Pantelis C, Papadimitriou GN, Parellada M, Paunio T, Pellegrino R, Periyasamy S, Perkins DO, Pfuhlmann B, Pietiläinen O, Pimm J, Porteous D, Powell J, Quattrone D, Quested D, Radant AD, Rampino A, Rapaport MH, Rautanen A, Reichenberg A, Roe C, Roffman JL, Roth J, Rothermundt M, Rutten BPF, Saker-Delye S, Salomaa V, Sanjuan J, Santoro ML, Savitz A, Schall U, Scott RJ, Seidman LJ, Sharp SI, Shi J, Siever LJ, Sigurdsson E, Sim K, Skarabis N, Slominsky P, So HC, Sobell JL, Söderman E, Stain HJ, Steen NE, Steixner-Kumar AA, Stögmann E, Stone WS, Straub RE, Streit F, Strengman E, Stroup TS, Subramaniam M, Sugar CA, Suvisaari J, Svrakic DM, Swerdlow NR, Szatkiewicz JP, Ta TMT, Takahashi A, Terao C, Thibaut F, Toncheva D, Tooney PA, Torretta S, Tosato S, Tura GB, Turetsky BI, Üçok A, Vaaler A, van Amelsvoort T, van Winkel R, Veijola J, Waddington J, Walter H, Waterreus A, Webb BT, Weiser M, Williams NM, Witt SH, Wormley BK, Wu JQ, Xu Z, Yolken R, Zai CC, Zhou W, Zhu F, Zimprich F, Atbaşoğlu EC, Ayub M, Benner C, Bertolino A, Black DW, Bray NJ, Breen G, Buccola NG, Byerley WF, Chen WJ, Cloninger CR, Crespo-Facorro B, Donohoe G, Freedman R, Galletly C, Gandal MJ, Gennarelli M, Hougaard DM, Hwu HG, Jablensky AV, McCarroll SA, Moran JL, Mors O, Mortensen PB, Müller-Myhsok B, Neil AL, Nordentoft M, Pato MT, Petryshen TL, Pirinen M, Pulver AE, Schulze TG, Silverman JM, Smoller JW, Stahl EA, Tsuang DW, Vilella E, Wang SH, Xu S, Indonesia Schizophrenia Consortium, PsychENCODE, Psychosis Endophenotypes International Consortium, SynGO Consortium, Adolfsson R, Arango C, Baune BT, Belangero SI, Børglum AD, Braff D, Bramon E, Buxbaum JD, Campion D, Cervilla JA, Cichon S, Collier DA, Corvin A, Curtis D, Forti MD, Domenici E, Ehrenreich H, Escott-Price V, Esko T, Fanous AH, Gareeva A, Gawlik M, Gejman PV, Gill M, Glatt SJ, Golimbet V, Hong KS, Hultman CM, Hyman SE, Iwata N, Jönsson EG, Kahn RS, Kennedy JL, Khusnutdinova E, Kirov G, Knowles JA, Krebs MO, Laurent-Levinson C, Lee J, Lencz T, Levinson DF, Li QS, Liu J, Malhotra AK, Malhotra D, McIntosh A, McQuillin A, Menezes PR, Morgan VA, Morris DW, Mowry BJ, Murray RM, Nimgaonkar V, Nöthen MM, Ophoff RA, Paciga SA, Palotie A, Pato CN, Qin S, Rietschel M, Riley BP, Rivera M, Rujescu D, Saka MC, Sanders AR, Schwab SG, Serretti A, Sham PC, Shi Y, St Clair D, Stefánsson H, Stefansson K, Tsuang MT, van Os J, Vawter MP, Weinberger DR, Werge T, Wildenauer DB, Yu X, Yue W, Holmans PA, Pocklington AJ, Roussos P, Vassos E, Verhage M, Visscher PM, Yang J, Posthuma D, Andreassen OA, Kendler KS, Owen MJ, Wray NR, Daly MJ, Huang H, Neale BM, Sullivan PF, Ripke S, Walters JTR, O'Donovan MC, Schizophrenia Working Group of the Psychiatric Genomics Consortium
• Human Astrocytes Exhibit Tumor Microenvironment-, Age-, and Sex-Related Transcriptomic Signatures.
  The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022 Feb 23;42(8):1587-1603 Epub 2022 Jan 5; Authors: Krawczyk MC, Haney JR, Pan L, Caneda C, Khankan RR, Reyes SD, Chang JW, Morselli M, Vinters HV, Wang AC, Cobos I, Gandal MJ, Bergsneider M, Kim W, Liau LM, Yong W, Jalali A, Deneen B, Grant GA, Mathern GW, Fallah A, Zhang Y
• Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.
  Biological psychiatry. 2022 Feb 1;91(3):313-327 Epub 2021 Sep 9; Authors: Mullins N, Kang J, Campos AI, Coleman JRI, Edwards AC, Galfalvy H, Levey DF, Lori A, Shabalin A, Starnawska A, Su MH, Watson HJ, Adams M, Awasthi S, Gandal M, Hafferty JD, Hishimoto A, Kim M, Okazaki S, Otsuka I, Ripke S, Ware EB, Bergen AW, Berrettini WH, Bohus M, Brandt H, Chang X, Chen WJ, Chen HC, Crawford S, Crow S, DiBlasi E, Duriez P, Fernández-Aranda F, Fichter MM, Gallinger S, Glatt SJ, Gorwood P, Guo Y, Hakonarson H, Halmi KA, Hwu HG, Jain S, Jamain S, Jiménez-Murcia S, Johnson C, Kaplan AS, Kaye WH, Keel PK, Kennedy JL, Klump KL, Li D, Liao SC, Lieb K, Lilenfeld L, Liu CM, Magistretti PJ, Marshall CR, Mitchell JE, Monson ET, Myers RM, Pinto D, Powers A, Ramoz N, Roepke S, Rozanov V, Scherer SW, Schmahl C, Sokolowski M, Strober M, Thornton LM, Treasure J, Tsuang MT, Witt SH, Woodside DB, Yilmaz Z, Zillich L, Adolfsson R, Agartz I, Air TM, Alda M, Alfredsson L, Andreassen OA, Anjorin A, Appadurai V, Soler Artigas M, Van der Auwera S, Azevedo MH, Bass N, Bau CHD, Baune BT, Bellivier F, Berger K, Biernacka JM, Bigdeli TB, Binder EB, Boehnke M, Boks MP, Bosch R, Braff DL, Bryant R, Budde M, Byrne EM, Cahn W, Casas M, Castelao E, Cervilla JA, Chaumette B, Cichon S, Corvin A, Craddock N, Craig D, Degenhardt F, Djurovic S, Edenberg HJ, Fanous AH, Foo JC, Forstner AJ, Frye M, Fullerton JM, Gatt JM, Gejman PV, Giegling I, Grabe HJ, Green MJ, Grevet EH, Grigoroiu-Serbanescu M, Gutierrez B, Guzman-Parra J, Hamilton SP, Hamshere ML, Hartmann A, Hauser J, Heilmann-Heimbach S, Hoffmann P, Ising M, Jones I, Jones LA, Jonsson L, Kahn RS, Kelsoe JR, Kendler KS, Kloiber S, Koenen KC, Kogevinas M, Konte B, Krebs MO, Landén M, Lawrence J, Leboyer M, Lee PH, Levinson DF, Liao C, Lissowska J, Lucae S, Mayoral F, McElroy SL, McGrath P, McGuffin P, McQuillin A, Medland SE, Mehta D, Melle I, Milaneschi Y, Mitchell PB, Molina E, Morken G, Mortensen PB, Müller-Myhsok B, Nievergelt C, Nimgaonkar V, Nöthen MM, O'Donovan MC, Ophoff RA, Owen MJ, Pato C, Pato MT, Penninx BWJH, Pimm J, Pistis G, Potash JB, Power RA, Preisig M, Quested D, Ramos-Quiroga JA, Reif A, Ribasés M, Richarte V, Rietschel M, Rivera M, Roberts A, Roberts G, Rouleau GA, Rovaris DL, Rujescu D, Sánchez-Mora C, Sanders AR, Schofield PR, Schulze TG, Scott LJ, Serretti A, Shi J, Shyn SI, Sirignano L, Sklar P, Smeland OB, Smoller JW, Sonuga-Barke EJS, Spalletta G, Strauss JS, Świątkowska B, Trzaskowski M, Turecki G, Vilar-Ribó L, Vincent JB, Völzke H, Walters JTR, Shannon Weickert C, Weickert TW, Weissman MM, Williams LM, Wray NR, Zai CC, Ashley-Koch AE, Beckham JC, Hauser ER, Hauser MA, Kimbrel NA, Lindquist JH, McMahon B, Oslin DW, Qin X, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, MVP Suicide Exemplar Workgroup, VA Million Veteran Program, Agerbo E, Børglum AD, Breen G, Erlangsen A, Esko T, Gelernter J, Hougaard DM, Kessler RC, Kranzler HR, Li QS, Martin NG, McIntosh AM, Mors O, Nordentoft M, Olsen CM, Porteous D, Ursano RJ, Wasserman D, Werge T, Whiteman DC, Bulik CM, Coon H, Demontis D, Docherty AR, Kuo PH, Lewis CM, Mann JJ, Rentería ME, Smith DJ, Stahl EA, Stein MB, Streit F, Willour V, Ruderfer DM
• Maternal Immune Activation during Pregnancy Alters Postnatal Brain Growth and Cognitive Development in Nonhuman Primate Offspring.
  The Journal of neuroscience : the official journal of the Society for Neuroscience. 2021 Dec 1;41(48):9971-9987 Epub 2021 Oct 4; Authors: Vlasova RM, Iosif AM, Ryan AM, Funk LH, Murai T, Chen S, Lesh TA, Rowland DJ, Bennett J, Hogrefe CE, Maddock RJ, Gandal MJ, Geschwind DH, Schumann CM, Van de Water J, McAllister AK, Carter CS, Styner MA, Amaral DG, Bauman MD
• Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors.
  Nature communications. 2021 Nov 16;12(1):6617; Authors: Krebs MD, Themudo GE, Benros ME, Mors O, Børglum AD, Hougaard D, Mortensen PB, Nordentoft M, Gandal MJ, Fan CC, Geschwind DH, Schork AJ, Werge T, Thompson WK
• Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing.
  Cell reports. 2021 Nov 16;37(7):110022; Authors: Leung SK, Jeffries AR, Castanho I, Jordan BT, Moore K, Davies JP, Dempster EL, Bray NJ, O'Neill P, Tseng E, Ahmed Z, Collier DA, Jeffery ED, Prabhakar S, Schalkwyk L, Jops C, Gandal MJ, Sheynkman GM, Hannon E, Mill J
• Identification of neural oscillations and epileptiform changes in human brain organoids.
  Nature neuroscience. 2021 Oct;24(10):1488-1500 Epub 2021 Aug 23; Authors: Samarasinghe RA, Miranda OA, Buth JE, Mitchell S, Ferando I, Watanabe M, Allison TF, Kurdian A, Fotion NN, Gandal MJ, Golshani P, Plath K, Lowry WE, Parent JM, Mody I, Novitch BG
• Postnatal immune activation causes social deficits in a mouse model of tuberous sclerosis: Role of microglia and clinical implications.
  Science advances. 2021 Sep 17;7(38):eabf2073; Authors: López-Aranda MF, Chattopadhyay I, Boxx GM, Fraley ER, Silva TK, Zhou M, Phan M, Herrera I, Taloma S, Mandanas R, Bach K, Gandal M, Geschwind DH, Cheng G, Rzhetsky A, White SA, Silva AJ
• Quantum computing at the frontiers of biological sciences.
  Nature methods. 2021 Jul;18(7):701-709; Authors: Emani PS, Warrell J, Anticevic A, Bekiranov S, Gandal M, McConnell MJ, Sapiro G, Aspuru-Guzik A, Baker JT, Bastiani M, Murray JD, Sotiropoulos SN, Taylor J, Senthil G, Lehner T, Gerstein MB, Harrow AW
• Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders.
  Nature communications. 2021 Jun 25;12(1):3968; Authors: Hu B, Won H, Mah W, Park RB, Kassim B, Spiess K, Kozlenkov A, Crowley CA, Pochareddy S, PsychENCODE Consortium, Li Y, Dracheva S, Sestan N, Akbarian S, Geschwind DH
• Brain gene co-expression networks link complement signaling with convergent synaptic pathology in schizophrenia.
  Nature neuroscience. 2021 Jun;24(6):799-809 Epub 2021 May 6; Authors: Kim M, Haney JR, Zhang P, Hernandez LM, Wang LK, Perez-Cano L, Loohuis LMO, de la Torre-Ubieta L, Gandal MJ
• Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
  Nature genetics. 2021 Jun;53(6):817-829 Epub 2021 May 17; Authors: Mullins N, Forstner AJ, O'Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, Børte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, Kamitaki N, Kim M, Krebs K, Panagiotaropoulou G, Schilder BM, Sloofman LG, Steinberg S, Trubetskoy V, Winsvold BS, Won HH, Abramova L, Adorjan K, Agerbo E, Al Eissa M, Albani D, Alliey-Rodriguez N, Anjorin A, Antilla V, Antoniou A, Awasthi S, Baek JH, Bækvad-Hansen M, Bass N, Bauer M, Beins EC, Bergen SE, Birner A, Bøcker Pedersen C, Bøen E, Boks MP, Bosch R, Brum M, Brumpton BM, Brunkhorst-Kanaan N, Budde M, Bybjerg-Grauholm J, Byerley W, Cairns M, Casas M, Cervantes P, Clarke TK, Cruceanu C, Cuellar-Barboza A, Cunningham J, Curtis D, Czerski PM, Dale AM, Dalkner N, David FS, Degenhardt F, Djurovic S, Dobbyn AL, Douzenis A, Elvsåshagen T, Escott-Price V, Ferrier IN, Fiorentino A, Foroud TM, Forty L, Frank J, Frei O, Freimer NB, Frisén L, Gade K, Garnham J, Gelernter J, Giørtz Pedersen M, Gizer IR, Gordon SD, Gordon-Smith K, Greenwood TA, Grove J, Guzman-Parra J, Ha K, Haraldsson M, Hautzinger M, Heilbronner U, Hellgren D, Herms S, Hoffmann P, Holmans PA, Huckins L, Jamain S, Johnson JS, Kalman JL, Kamatani Y, Kennedy JL, Kittel-Schneider S, Knowles JA, Kogevinas M, Koromina M, Kranz TM, Kranzler HR, Kubo M, Kupka R, Kushner SA, Lavebratt C, Lawrence J, Leber M, Lee HJ, Lee PH, Levy SE, Lewis C, Liao C, Lucae S, Lundberg M, MacIntyre DJ, Magnusson SH, Maier W, Maihofer A, Malaspina D, Maratou E, Martinsson L, Mattheisen M, McCarroll SA, McGregor NW, McGuffin P, McKay JD, Medeiros H, Medland SE, Millischer V, Montgomery GW, Moran JL, Morris DW, Mühleisen TW, O'Brien N, O'Donovan C, Olde Loohuis LM, Oruc L, Papiol S, Pardiñas AF, Perry A, Pfennig A, Porichi E, Potash JB, Quested D, Raj T, Rapaport MH, DePaulo JR, Regeer EJ, Rice JP, Rivas F, Rivera M, Roth J, Roussos P, Ruderfer DM, Sánchez-Mora C, Schulte EC, Senner F, Sharp S, Shilling PD, Sigurdsson E, Sirignano L, Slaney C, Smeland OB, Smith DJ, Sobell JL, Søholm Hansen C, Soler Artigas M, Spijker AT, Stein DJ, Strauss JS, Świątkowska B, Terao C, Thorgeirsson TE, Toma C, Tooney P, Tsermpini EE, Vawter MP, Vedder H, Walters JTR, Witt SH, Xi S, Xu W, Yang JMK, Young AH, Young H, Zandi PP, Zhou H, Zillich L, HUNT All-In Psychiatry, Adolfsson R, Agartz I, Alda M, Alfredsson L, Babadjanova G, Backlund L, Baune BT, Bellivier F, Bengesser S, Berrettini WH, Blackwood DHR, Boehnke M, Børglum AD, Breen G, Carr VJ, Catts S, Corvin A, Craddock N, Dannlowski U, Dikeos D, Esko T, Etain B, Ferentinos P, Frye M, Fullerton JM, Gawlik M, Gershon ES, Goes FS, Green MJ, Grigoroiu-Serbanescu M, Hauser J, Henskens F, Hillert J, Hong KS, Hougaard DM, Hultman CM, Hveem K, Iwata N, Jablensky AV, Jones I, Jones LA, Kahn RS, Kelsoe JR, Kirov G, Landén M, Leboyer M, Lewis CM, Li QS, Lissowska J, Lochner C, Loughland C, Martin NG, Mathews CA, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Melle I, Michie P, Milani L, Mitchell PB, Morken G, Mors O, Mortensen PB, Mowry B, Müller-Myhsok B, Myers RM, Neale BM, Nievergelt CM, Nordentoft M, Nöthen MM, O'Donovan MC, Oedegaard KJ, Olsson T, Owen MJ, Paciga SA, Pantelis C, Pato C, Pato MT, Patrinos GP, Perlis RH, Posthuma D, Ramos-Quiroga JA, Reif A, Reininghaus EZ, Ribasés M, Rietschel M, Ripke S, Rouleau GA, Saito T, Schall U, Schalling M, Schofield PR, Schulze TG, Scott LJ, Scott RJ, Serretti A, Shannon Weickert C, Smoller JW, Stefansson H, Stefansson K, Stordal E, Streit F, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Waldman ID, Weickert TW, Werge T, Wray NR, Zwart JA, Biernacka JM, Nurnberger JI, Cichon S, Edenberg HJ, Stahl EA, McQuillin A, Di Florio A, Ophoff RA, Andreassen OA
• Leveraging eQTLs to identify individual-level tissue of interest for a complex trait.
  PLoS computational biology. 2021 May;17(5):e1008915 Epub 2021 May 21; Authors: Majumdar A, Giambartolomei C, Cai N, Haldar T, Schwarz T, Gandal M, Flint J, Pasaniuc B
• Alterations in Retrotransposition, Synaptic Connectivity, and Myelination Implicated by Transcriptomic Changes Following Maternal Immune Activation in Nonhuman Primates.
  Biological psychiatry. 2021 May 1;89(9):896-910 Epub 2020 Nov 2; Authors: Page NF, Gandal MJ, Estes ML, Cameron S, Buth J, Parhami S, Ramaswami G, Murray K, Amaral DG, Van de Water JA, Schumann CM, Carter CS, Bauman MD, McAllister AK, Geschwind DH
• Transcriptomic Insight Into the Polygenic Mechanisms Underlying Psychiatric Disorders.
  Biological psychiatry. 2021 Jan 1;89(1):54-64 Epub 2020 Jun 12; Authors: Hernandez LM, Kim M, Hoftman GD, Haney JR, de la Torre-Ubieta L, Pasaniuc B, Gandal MJ
• Polygenicity in Psychiatry-Like It or Not, We Have to Understand It.
  Biological psychiatry. 2021 Jan 1;89(1):2-4; Authors: Gandal MJ, Geschwind DH
• Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism.
  Nature communications. 2020 Sep 25;11(1):4873; Authors: Ramaswami G, Won H, Gandal MJ, Haney J, Wang JC, Wong CCY, Sun W, Prabhakar S, Mill J, Geschwind DH
• Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms.
  Cell. 2020 Apr 30;181(3):745; Authors: Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, de la Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH
• Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms.
  Cell. 2020 Apr 16;181(2):484; Authors: Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH
• Synaptic and Gene Regulatory Mechanisms in Schizophrenia, Autism, and 22q11.2 Copy Number Variant-Mediated Risk for Neuropsychiatric Disorders.
  Biological psychiatry. 2020 Jan 15;87(2):150-163 Epub 2019 Jul 11; Authors: Forsyth JK, Nachun D, Gandal MJ, Geschwind DH, Anderson AE, Coppola G, Bearden CE
• A Robust Method Uncovers Significant Context-Specific Heritability in Diverse Complex Traits.
  American journal of human genetics. 2020 Jan 2;106(1):71-91; Authors: Dahl A, Nguyen K, Cai N, Gandal MJ, Flint J, Zaitlen N
• Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms.
  Cell. 2019 Oct 17;179(3):750-771.e22; Authors: Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, de la Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH
• Mechanisms of Neuronal Alternative Splicing and Strategies for Therapeutic Interventions.
  The Journal of neuroscience : the official journal of the Society for Neuroscience. 2019 Oct 16;39(42):8193-8199; Authors: Lopez Soto EJ, Gandal MJ, Gonatopoulos-Pournatzis T, Heller EA, Luo D, Zheng S
• Profiling allele-specific gene expression in brains from individuals with autism spectrum disorder reveals preferential minor allele usage.
  Nature neuroscience. 2019 Sep;22(9):1521-1532 Epub 2019 Aug 26; Authors: Lee C, Kang EY, Gandal MJ, Eskin E, Geschwind DH
• Inherited and De Novo Genetic Risk for Autism Impacts Shared Networks.
  Cell. 2019 Aug 8;178(4):850-866.e26; Authors: Ruzzo EK, Pérez-Cano L, Jung JY, Wang LK, Kashef-Haghighi D, Hartl C, Singh C, Xu J, Hoekstra JN, Leventhal O, Leppä VM, Gandal MJ, Paskov K, Stockham N, Polioudakis D, Lowe JK, Prober DA, Geschwind DH, Wall DP
• Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice.
  Cell. 2019 May 30;177(6):1600-1618.e17; Authors: Sharon G, Cruz NJ, Kang DW, Gandal MJ, Wang B, Kim YM, Zink EM, Casey CP, Taylor BC, Lane CJ, Bramer LM, Isern NG, Hoyt DW, Noecker C, Sweredoski MJ, Moradian A, Borenstein E, Jansson JK, Knight R, Metz TO, Lois C, Geschwind DH, Krajmalnik-Brown R, Mazmanian SK
• Integrative network analysis reveals biological pathways associated with Williams syndrome.
  Journal of child psychology and psychiatry, and allied disciplines. 2019 May;60(5):585-598 Epub 2018 Oct 25; Authors: Kimura R, Swarup V, Tomiwa K, Gandal MJ, Parikshak NN, Funabiki Y, Nakata M, Awaya T, Kato T, Iida K, Okazaki S, Matsushima K, Kato T, Murai T, Heike T, Geschwind DH, Hagiwara M
• A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment.
  Nature neuroscience. 2019 Mar;22(3):353-361 Epub 2019 Jan 28; Authors: Schork AJ, Won H, Appadurai V, Nudel R, Gandal M, Delaneau O, Revsbech Christiansen M, Hougaard DM, Bækved-Hansen M, Bybjerg-Grauholm J, Giørtz Pedersen M, Agerbo E, Bøcker Pedersen C, Neale BM, Daly MJ, Wray NR, Nordentoft M, Mors O, Børglum AD, Bo Mortensen P, Buil A, Thompson WK, Geschwind DH, Werge T
• Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.
  Nature genetics. 2019 Jan;51(1):63-75 Epub 2018 Nov 26; Authors: Demontis D, Walters RK, Martin J, Mattheisen M, Als TD, Agerbo E, Baldursson G, Belliveau R, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Churchhouse C, Dumont A, Eriksson N, Gandal M, Goldstein JI, Grasby KL, Grove J, Gudmundsson OO, Hansen CS, Hauberg ME, Hollegaard MV, Howrigan DP, Huang H, Maller JB, Martin AR, Martin NG, Moran J, Pallesen J, Palmer DS, Pedersen CB, Pedersen MG, Poterba T, Poulsen JB, Ripke S, Robinson EB, Satterstrom FK, Stefansson H, Stevens C, Turley P, Walters GB, Won H, Wright MJ, ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, 23andMe Research Team, Andreassen OA, Asherson P, Burton CL, Boomsma DI, Cormand B, Dalsgaard S, Franke B, Gelernter J, Geschwind D, Hakonarson H, Haavik J, Kranzler HR, Kuntsi J, Langley K, Lesch KP, Middeldorp C, Reif A, Rohde LA, Roussos P, Schachar R, Sklar P, Sonuga-Barke EJS, Sullivan PF, Thapar A, Tung JY, Waldman ID, Medland SE, Stefansson K, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Daly MJ, Faraone SV, Børglum AD, Neale BM
• Shared Molecular Neuropathology Across Major Psychiatric Disorders Parallels Polygenic Overlap.
  Focus (American Psychiatric Publishing). 2019 Jan;17(1):66-72 Epub 2019 Jan 7; Authors: Gandal MJ, Haney JR, Parikshak NN, Leppa V, Ramaswami G, Hartl C, Schork AJ, Appadurai V, Buil A, Werge TM, Liu C, White KP, CommonMind Consortium, PsychENCODE Consortium, iPSYCH-BROAD Working Group, Steve Horvath, Geschwind DH
• Transcriptome and epigenome landscape of human cortical development modeled in organoids.
  Science (New York, N.Y.). 2018 Dec 14;362(6420); Authors: Amiri A, Coppola G, Scuderi S, Wu F, Roychowdhury T, Liu F, Pochareddy S, Shin Y, Safi A, Song L, Zhu Y, Sousa AMM, PsychENCODE Consortium, Gerstein M, Crawford GE, Sestan N, Abyzov A, Vaccarino FM
• Integrative functional genomic analysis of human brain development and neuropsychiatric risks.
  Science (New York, N.Y.). 2018 Dec 14;362(6420); Authors: Li M, Santpere G, Imamura Kawasawa Y, Evgrafov OV, Gulden FO, Pochareddy S, Sunkin SM, Li Z, Shin Y, Zhu Y, Sousa AMM, Werling DM, Kitchen RR, Kang HJ, Pletikos M, Choi J, Muchnik S, Xu X, Wang D, Lorente-Galdos B, Liu S, Giusti-Rodríguez P, Won H, de Leeuw CA, Pardiñas AF, BrainSpan Consortium, PsychENCODE Consortium, PsychENCODE Developmental Subgroup, Hu M, Jin F, Li Y, Owen MJ, O'Donovan MC, Walters JTR, Posthuma D, Reimers MA, Levitt P, Weinberger DR, Hyde TM, Kleinman JE, Geschwind DH, Hawrylycz MJ, State MW, Sanders SJ, Sullivan PF, Gerstein MB, Lein ES, Knowles JA, Sestan N
• Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder.
  Science (New York, N.Y.). 2018 Dec 14;362(6420); Authors: Gandal MJ, Zhang P, Hadjimichael E, Walker RL, Chen C, Liu S, Won H, van Bakel H, Varghese M, Wang Y, Shieh AW, Haney J, Parhami S, Belmont J, Kim M, Moran Losada P, Khan Z, Mleczko J, Xia Y, Dai R, Wang D, Yang YT, Xu M, Fish K, Hof PR, Warrell J, Fitzgerald D, White K, Jaffe AE, PsychENCODE Consortium, Peters MA, Gerstein M, Liu C, Iakoucheva LM, Pinto D, Geschwind DH
• Comprehensive functional genomic resource and integrative model for the human brain.
  Science (New York, N.Y.). 2018 Dec 14;362(6420); Authors: Wang D, Liu S, Warrell J, Won H, Shi X, Navarro FCP, Clarke D, Gu M, Emani P, Yang YT, Xu M, Gandal MJ, Lou S, Zhang J, Park JJ, Yan C, Rhie SK, Manakongtreecheep K, Zhou H, Nathan A, Peters M, Mattei E, Fitzgerald D, Brunetti T, Moore J, Jiang Y, Girdhar K, Hoffman GE, Kalayci S, Gümüş ZH, Crawford GE, PsychENCODE Consortium, Roussos P, Akbarian S, Jaffe AE, White KP, Weng Z, Sestan N, Geschwind DH, Knowles JA, Gerstein MB
• Revealing the brain's molecular architecture.
  Science (New York, N.Y.). 2018 Dec 14;362(6420):1262-1263; Authors: PsychENCODE Consortium
• Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia.
  Nature communications. 2018 Dec 13;9(1):5296; Authors: Fan CC, McGrath JJ, Appadurai V, Buil A, Gandal MJ, Schork AJ, Mortensen PB, Agerbo E, Geschwind SA, Geschwind D, Werge T, Thompson WK, Pedersen CB
• Author Correction: Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism.
  Nature. 2018 Aug;560(7718):E30; Authors: Parikshak NN, Swarup V, Belgard TG, Irimia M, Ramaswami G, Gandal MJ, Hartl C, Leppa V, de la Torre Ubieta L, Huang J, Lowe JK, Blencowe BJ, Horvath S, Geschwind DH
• Banking on Polygenicity to Disentangle Psychiatric Comorbidity.
  Biological psychiatry. Cognitive neuroscience and neuroimaging. 2018 Jul;3(7):577-578; Authors: Haney JR, Parhami S, Gandal MJ
• Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex.
  Journal of neurodevelopmental disorders. 2018 Jun 1;10(1):18; Authors: Schwede M, Nagpal S, Gandal MJ, Parikshak NN, Mirnics K, Geschwind DH, Morrow EM
• Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap.
  Science (New York, N.Y.). 2018 Feb 9;359(6376):693-697; Authors: Gandal MJ, Haney JR, Parikshak NN, Leppa V, Ramaswami G, Hartl C, Schork AJ, Appadurai V, Buil A, Werge TM, Liu C, White KP, CommonMind Consortium, PsychENCODE Consortium, iPSYCH-BROAD Working Group, Horvath S, Geschwind DH
• The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability.
  Nature genetics. 2017 Aug;49(8):1167-1173 Epub 2017 Jun 26; Authors: Singh T, Walters JTR, Johnstone M, Curtis D, Suvisaari J, Torniainen M, Rees E, Iyegbe C, Blackwood D, McIntosh AM, Kirov G, Geschwind D, Murray RM, Di Forti M, Bramon E, Gandal M, Hultman CM, Sklar P, INTERVAL Study, UK10K Consortium, Palotie A, Sullivan PF, O'Donovan MC, Owen MJ, Barrett JC
• Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism.
  Nature. 2016 Dec 15;540(7633):423-427 Epub 2016 Dec 5; Authors: Parikshak NN, Swarup V, Belgard TG, Irimia M, Ramaswami G, Gandal MJ, Hartl C, Leppa V, Ubieta LT, Huang J, Lowe JK, Blencowe BJ, Horvath S, Geschwind DH
• Chromosome conformation elucidates regulatory relationships in developing human brain.
  Nature. 2016 Oct 27;538(7626):523-527 Epub 2016 Oct 19; Authors: Won H, de la Torre-Ubieta L, Stein JL, Parikshak NN, Huang J, Opland CK, Gandal MJ, Sutton GJ, Hormozdiari F, Lu D, Lee C, Eskin E, Voineagu I, Ernst J, Geschwind DH
• The road to precision psychiatry: translating genetics into disease mechanisms.
  Nature neuroscience. 2016 Oct 26;19(11):1397-1407; Authors: Gandal MJ, Leppa V, Won H, Parikshak NN, Geschwind DH
• The Genetics-Driven Revival in Neuropsychiatric Drug Development.
  Biological psychiatry. 2016 Apr 15;79(8):628-30; Authors: Gandal MJ, Geschwind DH
• Cannabis-induced psychosis associated with high potency "wax dabs".
  Schizophrenia research. 2016 Apr;172(1-3):211-2 Epub 2016 Feb 11; Authors: Pierre JM, Gandal M, Son M
• Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders.
  Nature reviews. Genetics. 2015 Aug;16(8):441-58 Epub 2015 Jul 7; Authors: Parikshak NN, Gandal MJ, Geschwind DH
• Pyramidal cell selective ablation of N-methyl-D-aspartate receptor 1 causes increase in cellular and network excitability.
  Biological psychiatry. 2015 Mar 15;77(6):556-68 Epub 2014 Jul 18; Authors: Tatard-Leitman VM, Jutzeler CR, Suh J, Saunders JA, Billingslea EN, Morita S, White R, Featherstone RE, Ray R, Ortinski PI, Banerjee A, Gandal MJ, Lin R, Alexandrescu A, Liang Y, Gur RE, Borgmann-Winter KE, Carlson GC, Hahn CG, Siegel SJ
• Convergence of circuit dysfunction in ASD: a common bridge between diverse genetic and environmental risk factors and common clinical electrophysiology.
  Frontiers in cellular neuroscience. 2014;8:414 Epub 2014 Dec 8; Authors: Port RG, Gandal MJ, Roberts TP, Siegel SJ, Carlson GC
• Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2014 Jun;39(7):1603-13 Epub 2014 Feb 14; Authors: Billingslea EN, Tatard-Leitman VM, Anguiano J, Jutzeler CR, Suh J, Saunders JA, Morita S, Featherstone RE, Ortinski PI, Gandal MJ, Lin R, Liang Y, Gur RE, Carlson GC, Hahn CG, Siegel SJ
• NMDA antagonist MK801 recreates auditory electrophysiology disruption present in autism and other neurodevelopmental disorders.
  Behavioural brain research. 2012 Oct 1;234(2):233-7 Epub 2012 Jul 5; Authors: Saunders JA, Gandal MJ, Roberts TP, Siegel SJ
• Mice with reduced NMDA receptor expression: more consistent with autism than schizophrenia?
  Genes, brain, and behavior. 2012 Aug;11(6):740-50; Authors: Gandal MJ, Anderson RL, Billingslea EN, Carlson GC, Roberts TP, Siegel SJ
• GABAB-mediated rescue of altered excitatory-inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction.
  Translational psychiatry. 2012 Jul 17;2(7):e142; Authors: Gandal MJ, Sisti J, Klook K, Ortinski PI, Leitman V, Liang Y, Thieu T, Anderson R, Pierce RC, Jonak G, Gur RE, Carlson G, Siegel SJ
• NMDA antagonists recreate signal-to-noise ratio and timing perturbations present in schizophrenia.
  Neurobiology of disease. 2012 Apr;46(1):93-100 Epub 2012 Jan 9; Authors: Saunders JA, Gandal MJ, Siegel SJ
• MeCP2+/- mouse model of RTT reproduces auditory phenotypes associated with Rett syndrome and replicate select EEG endophenotypes of autism spectrum disorder.
  Neurobiology of disease. 2012 Apr;46(1):88-92 Epub 2012 Jan 9; Authors: Liao W, Gandal MJ, Ehrlichman RS, Siegel SJ, Carlson GC
• Nicotine normalizes event related potentials in COMT-Val-tg mice and increases gamma and theta spectral density.
  Behavioral neuroscience. 2012 Apr;126(2):332-43 Epub 2012 Feb 6; Authors: Cao YA, Featherstone RE, Gandal MJ, Liang Y, Jutzeler C, Saunders J, Tatard-Leitman V, Chen J, Weinberger DR, Lerman C, Siegel SJ
• Gamma synchrony: towards a translational biomarker for the treatment-resistant symptoms of schizophrenia.
  Neuropharmacology. 2012 Mar;62(3):1504-18 Epub 2011 Feb 22; Authors: Gandal MJ, Edgar JC, Klook K, Siegel SJ
• Measuring the maturity of the fast-spiking interneuron transcriptional program in autism, schizophrenia, and bipolar disorder.
  PloS one. 2012;7(8):e41215 Epub 2012 Aug 24; Authors: Gandal MJ, Nesbitt AM, McCurdy RM, Alter MD
• Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia.
  Proceedings of the National Academy of Sciences of the United States of America. 2011 Oct 25;108(43):E962-70 Epub 2011 Oct 3; Authors: Carlson GC, Talbot K, Halene TB, Gandal MJ, Kazi HA, Schlosser L, Phung QH, Gur RE, Arnold SE, Siegel SJ
• mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism.
  PloS one. 2011;6(10):e26077 Epub 2011 Oct 7; Authors: Mehta MV, Gandal MJ, Siegel SJ
• Validating γ oscillations and delayed auditory responses as translational biomarkers of autism.
  Biological psychiatry. 2010 Dec 15;68(12):1100-6; Authors: Gandal MJ, Edgar JC, Ehrlichman RS, Mehta M, Roberts TP, Siegel SJ
• Mouse behavioral endophenotypes for schizophrenia.
  Brain research bulletin. 2010 Sep 30;83(3-4):147-61 Epub 2010 Apr 28; Authors: Amann LC, Gandal MJ, Halene TB, Ehrlichman RS, White SL, McCarren HS, Siegel SJ
• In vitro-in vivo correlations of scalable PLGA-risperidone implants for the treatment of schizophrenia.
  Pharmaceutical research. 2010 Aug;27(8):1730-7 Epub 2010 Apr 27; Authors: Amann LC, Gandal MJ, Lin R, Liang Y, Siegel SJ
• Ketamine modulates theta and gamma oscillations.
  Journal of cognitive neuroscience. 2010 Jul;22(7):1452-64; Authors: Lazarewicz MT, Ehrlichman RS, Maxwell CR, Gandal MJ, Finkel LH, Siegel SJ
• MEG detection of delayed auditory evoked responses in autism spectrum disorders: towards an imaging biomarker for autism.
  Autism research : official journal of the International Society for Autism Research. 2010 Feb;3(1):8-18; Authors: Roberts TP, Khan SY, Rey M, Monroe JF, Cannon K, Blaskey L, Woldoff S, Qasmieh S, Gandal M, Schmidt GL, Zarnow DM, Levy SE, Edgar JC
• N-methyl-d-aspartic acid receptor antagonist-induced frequency oscillations in mice recreate pattern of electrophysiological deficits in schizophrenia.
  Neuroscience. 2009 Jan 23;158(2):705-12 Epub 2008 Oct 28; Authors: Ehrlichman RS, Gandal MJ, Maxwell CR, Lazarewicz MT, Finkel LH, Contreras D, Turetsky BI, Siegel SJ
• A novel electrophysiological model of chemotherapy-induced cognitive impairments in mice.
  Neuroscience. 2008 Nov 11;157(1):95-104 Epub 2008 Sep 9; Authors: Gandal MJ, Ehrlichman RS, Rudnick ND, Siegel SJ
• Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control.
  The Journal of clinical investigation. 2004 May;113(9):1344-52; Authors: Karai L, Brown DC, Mannes AJ, Connelly ST, Brown J, Gandal M, Wellisch OM, Neubert JK, Olah Z, Iadarola MJ