The Gandal Lab @ Penn/CHOP

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Featured Publications

Featured

Gandal, Haney, Wamsley et al., Nature 2022
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Gandal, Haney, Wamsley et al., Nature 2022
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Gandal, M. J.*, Haney, J. R., Wamsley, B., Yap, C. X., Parhami, S., Emani, P. S., Chang, N., Chen, G. T., Hoftman, G. D., de Alba, D., Ramaswami, G., Hartl, C. L., Bhattacharya, A., Luo, C., Jin, T., Wang, D., Kawaguchi, R., Quintero, D., Ou, J., … Geschwind, D. H.* (2022). Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD. Nature, 611(7936), 532–539.
Gandal et al., Science 2018b
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Gandal et al., Science 2018b
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Gandal, M. J.*, Zhang, P., Hadjimichael, E., Walker, R. L., Chen, C., Liu, S., Won, H., van Bakel, H., Varghese, M., Wang, Y., Shieh, A. W., Haney, J., Parhami, S., Belmont, J., Kim, M., Moran Losada, P., Khan, Z., Mleczko, J., Xia, Y., … Geschwind, D. H.* (2018). Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder. Science, 362(6420).
Gandal et al., Science 2018a
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Gandal et al., Science 2018a
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Gandal, M. J., Haney, J. R., Parikshak, N. N., Leppa, V., Ramaswami, G., Hartl, C., Schork, A. J., Appadurai, V., Buil, A., Werge, T. M., Liu, C., White, K. P., CommonMind Consortium, PsychENCODE Consortium, iPSYCH-BROAD Working Group, Horvath, S., & Geschwind, D. H. (2018). Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap. Science, 359(6376), 693–697.
Kim M et al., Nat Neuro, 2021
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Kim M et al., Nat Neuro, 2021
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Kim, M., Haney, J. R., Zhang, P., Hernandez, L. M., Wang, L.-K., Perez-Cano, L., Loohuis, L. M. O., de la Torre-Ubieta, L., & Gandal, M. J. (2021). Brain gene co-expression networks link complement signaling with convergent synaptic pathology in schizophrenia. Nature Neuroscience, 24(6), 799–809.

2023

Zhang P et al., PNAS 2023
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Zhang P et al., PNAS 2023
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Pan Zhang, Alicja Omanska, Bradley P. Ander, Michael J. Gandal*, Boryana Stamovae*, and Cynthia M. Schuman* (2023) "Neuron-specific transcriptomic signatures indicate neuroinflammation and altered neuronal activity in ASD temporal cortex" PNAS.
Kim et al., Bioinformatics, 2023
https://github.com/mmkim1210/GeneticsMakie.jl
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Kim et al., Bioinformatics, 2023
https://github.com/mmkim1210/GeneticsMakie.jl
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Kim, M., Vo, D. D., Kumagai, M. E., Jops, C. T., & Gandal, M. J. (2023). GeneticsMakie.jl: a versatile and scalable toolkit for visualizing locus-level genetic and genomic data. Bioinformatics , 39(1).

Github: https://github.com/mmkim1210/GeneticsMakie.jl
Hernandez et al., Biol Psych GOS, 2023
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Hernandez et al., Biol Psych GOS, 2023
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Hernandez, L. M., Kim, M., Hernandez, C., Thompson, W., Fan, C. C., Galván, A., Dapretto, M., Bookheimer, S. Y., Fuligni, A., & Gandal, M. J. (2023). Decoupling Sleep and Brain Size in Childhood: An Investigation of Genetic Covariation in the Adolescent Brain Cognitive Development Study. Biological Psychiatry Global Open Science, 3(1), 139–148.

A link to all our publications on Google Scholar